THE TRACHEAL ASPIRATE LUNG PROFILE

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Tracheal aspirate pH is alkaline in pre-term human infants.

The pH of sputum and exhaled breath condensate is abnormal in several pulmonary disorders. Though airway pH regulatory proteins may be abnormally expressed in human development, the tracheal aspirate pH of infants born prematurely has not been studied. Undiluted mid-tracheal aspirate samples were obtained on the first day of life from pre-term (23-30 weeks' gestation) and term (> or =37 weeks' ...

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Tracheal Aspirate Levels of the Matricellular Protein SPARC Predict Development of Bronchopulmonary Dysplasia

BACKGROUND Isolation of tracheal aspirate mesenchymal stromal cells (MSCs) from premature infants has been associated with increased risk of bronchopulmonary dysplasia (BPD). MSCs show high levels of mRNAs encoding matricellular proteins, non-structural extracellular proteins that regulate cell-matrix interactions and participate in tissue remodeling. We hypothesized that lung matricellular pro...

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Tracheal aspirate correlates with protected specimen brush in long-term ventilated patients who have clinical pneumonia.

STUDY OBJECTIVE This study was undertaken to determine whether tracheal aspirate cultures correlate with protected specimen brush (PSB) cultures in the diagnosis of probable ventilator-associated pneumonia (VAP). DESIGN Retrospective evaluation of 52 episodes of clinical pneumonia in 38 patients who underwent bronchoscopy and PSB as well as tracheal aspirate cultures. SETTING The study took...

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Tracheal aspirate cultures in long-term ventilated patients who have clinical pneumonia.

I read with interest the article by Rumbak and colleagues (CHEST 1994; 106:531-34) in the August 1994 issue describing the correlation between the tracheal aspirate (TA) and protected specimen brush (PSB) cultures in stable long-term ventilatorassisted patients with the clinical diagnosis of pneumonia. No pa¬ tient had received antibiotics for the preceding 5 days at the time of bronchoscopy or...

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Accuracy of tracheal aspirate gram stain in predicting Staphylococcus aureus infection in ventilator-associated pneumonia

BACKGROUND The Gram stain can be used to direct initial empiric antimicrobial therapy when complete culture is not available. This rapid test could prevent the initiation of inappropriate therapy and adverse outcomes. However, several studies have attempted to determine the value of the Gram stain in the diagnosis and therapy of bacterial infection in different populations of patients with vent...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1984

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-198404001-01492